Plasticity Effect: Skin elasticity is the capability of the skin to deform under the action of external forces and resume its shape when forces cease. Elastic fibers, by wrapping and connecting collagen fibers up, allow the skin to return to its starting shape after compression or relaxation. With the passing of time also the quantity and quality of elastin, the protein that makes up elastic fibres, drastically decreases thus threatening skin plasticity and contributing to skin sagging. Fillerina 932 Biorevitalizing associates 2 molecules of Elastin with different molecular weights (1400 Da and 2200 Da), which help restore skin elasticity and plasticity.
The skin is hardly permeable: in order for the Hyaluronic Acids, as well as other Fillerina functional molecules, to penetrate the different cutaneous layers, Labo researchers developed a Transdermic Technology based on the very low molecular weight of the active substances. This is the fundamental condition to guarantee their penetration in the cutaneous layers. It is precisely thanks to this controlled penetration that the active ingredients are really effective in terms of filling. The reported percentages refer to the transdermic penetration of Hyaluronic Acids and functional active molecules, in solution, after 24 hours. Transdermic penetration was made possible by the new Labo technology and tested by means of Franz Cells. The difference vs the theoretical value 100% represents the sum of experimental errors in the procedures applied in the study; these differences are considered acceptable and so insignificant that they do not affect the study results.
BIOREVITALIZING EFFECT: Besides Hyaluronic Acids, for a replenishing effect, Collagen and Elastin molecules, Fillerina 932 Biorevitalizing contains all necessary components for the vitality of the skin, which experiences, as time goes by, a drastic reduction in physiological processes, typical of an old skin.
The Biorevitalizing Complex contains 20 amino acids, 11 vitamins, 6 trace elements and 2 nucleic acids: their great penetration capability has been ex vivo tested by means of Franz Cells and depends on their low molecular weight. Thanks to this important feature, these substances can penetrate both epidermis and dermis (see table) thus giving the skin brightness, compactness, smoothness and splendor.
The molecular weight of the 20 amino acids ranges from 75 to 204 Dalton; that of the 11 vitamins (vit. A, C, E and B-Group) ranges from 122 to 1500 Dalton; the 6 trace elements (Calcium, Iron, Magnesium, Manganese, Copper and Zinc) have a molecular weight ranging from 95 to 162 Dalton; finally, the molecular weight of the 2 nucleic acids, Hydrolyzed DNA and RNA, is 660 and 330 Dalton respectively.
The Biorevitalizing Complex is contained in both Filler Gel and Nourishing Film.
THE GRADES: Fillerina 932 Biorevitalizing dermo-cosmetic filler treatments for at-home use have been formulated in 3 different concentrations (-Bio) containing differentiated blends of 9 Hyaluronic Acid molecules, 3 Collagens, 2 Elastins and of the Biorevitalizing Complex, to be chosen according to the individual needs.
GRADE 5-Bio: Very deep wrinkles and expression lines. Age wrinkles with very marked and uneven microrelief. Skin with insufficient thickness, density and plasticity. Dull complexion, damaged and shrivelled skin.
How To Use: Apply in the morning in the evening to see desired results.
Fillerina 932 Biorevitalizing – Gel – Ingredients: Aqua, Glycerin, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Caprylyl Glycol, Carbomer, Pentylene Glycol, Propylene Glycol, 1,2-Hexanediol, Hydrolyzed Collagen, Sodium PCA, Butylene Glycol, Sodium Lactate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Arginine, Phenoxyethanol, Hydrolyzed Sodium Hyaluronate, Aspartic Acid, PCA, Hyaluronic Acid, Tropolone, Sodium Chondroitin Sulfate, Decylene Glycol, Hydroxypropyl Cyclodextrin, Hydrolyzed DNA, Hydrolyzed RNA, Glycine, Palmitoyl Tripeptide-38, Alanine, Palmitoyl Hexapeptide-52, Serine, Valine, Hydrolyzed Elastin, Leuconostoc/Radish Root Ferment Filtrate, Isoleucine, Proline, Threonine, Soluble Collagen, Histidine, Phenylalanine, Glyceryl Caprylate, Calcium Chloride, Cupric Chloride, Ferric Chloride, Magnesium Chloride, Manganese Chloride, Palmitoyl Heptapeptide-18, Zinc Chloride, Phenylpropanol, Acetyl Hexapeptide-37, sh-Oligopeptide-1, Polyvinyl Alcohol, sh-Polypeptide-1, Acetyl Cysteine, Biotin/Folic Acid/Cyanocobalamin/Niacinamide/PantothenicAcid/Pyridoxine/Riboflavin/Thiamine/Yeast Polypeptide, Glutamic Acid, sh-Polypeptide-5, Glutamine, Leucine, Lysine HCl, Methionine, Taurine, Tryptophan, Tyrosine, Sorbitol, Retinyl Palmitate, Glyceryl Linoleate, Glyceryl Linolenate, Tocopheryl Acetate, Disodium EDTA, Sodium Benzoate, Ethylhexylglycerin, Glycine Soja (Soybean) Oil, Sodium Oleate, Hydrogenated Lecithin, Sodium Hydroxide, Xanthan Gum, Sodium Chloride, Sorbic Acid, Glycolic Acid, Sodium Ascorbyl Phosphate, Lactic Acid, Lecithin.
Fillerina 932 Biorevitalizing – Nourishing Film – Ingredients: Aqua, Cyclopentasiloxane, Glycerin, HDI/Trimethylol Hexyllactone Crosspolymer, Polysilicone-11, C30-45 Alkyl Cetearyl Dimethicone Crosspolymer, Dimethicone, Steareth-2, Xylitol, Hydrogenated Lecithin, Butylene Glycol, Steareth-21, Limnanthes Alba Seed Oil, Phenoxyethanol, Boron Nitride, Sodium Hyaluronate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Tocopheryl Acetate, Stearic Acid, Palmitic Acid, Benzophenone-3, Sodium Chloride, Diazolidinyl Urea, Parfum, Lecithin, Pseudoalteromonas Ferment Extract, Benzophenone-4, Allantoin, Butyrospermum Parkii Butter, Silica, Limonene, Sorbitol, Linalool, Hydrolyzed DNA, Hydrolyzed RNA, Hexyl Cinnamal, Acetyl Cysteine, Glutamic Acid, Glutamine, Leucine, Lysine HCl, Methionine, Taurine, Tryptophan, Tyrosine, Caprylyl Glycol, Butylphenyl Methylpropional, Glyceryl Linoleate, Glyceryl Linolenate, Geraniol, Citronellol, Retinyl Palmitate, Sodium Ascorbyl Phosphate, Arginine, Salicylic Acid, Coumarin, Citral, Biotin/Folic Acid/Cyanocobalamin/Niacinamide/Pantothenic Acid/Pyridoxine/Riboflavin/Thiamine/Yeast Polypeptide, Glyceryl Caprylate, Acetyl Hexapeptide-30, Sodium Lactate, Aspartic Acid, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Calcium Chloride, Cupric Chloride, Ferric Chloride, Magnesium Chloride, Zinc Chloride, Manganese Chloride, Propylene Glycol, Pentylene Glycol, Alcohol, PCA, Sodium PCA, BHT, Xanthan Gum, Sodium Hydroxide, Disodium EDTA.
Pre-Fillerina Skin Preparatory Cleanser – Ingredients: Aqua, Glycerin, Glyceryl Stearate SE, Cetearyl Alcohol, Cocamidopropyl Betaine, TEA-Lauryl Sulfate, Caprylic/Capric Triglyceride, Cetearyl Isononanoate, Glyceryl Stearate, Sucrose Laurate, Polyacrylamide, Tocopheryl Acetate, C13-14 Isoparaffin, Hyaluronic Acid, Laureth-7, Phenoxyethanol, Caprylyl Glycol, Parfum, Disodium EDTA, Tributyl Citrate, Tris(Tetramethylhydroxypiperidinol) Citrate, Sodium Benzotriazolyl Butylphenol Sulfonate, Buteth-3.